Exploring the influence of artificial intelligence technology on consumer repurchase intention: The mediation and moderation approach

Digital technologies have dramatically changed business practices and consumer buying behavior. This study integrates artificial intelligence technology, consumer engagement on social media, conversion rate optimiza-tion, and satisfying consumer experience to examine consumer repurchase intentions in the hospitality industry. Data was collected from 308 hotel customers from different regions of Oman who had an online hotel booking experience. SmartPLS was used to examine the data and proposed hypotheses. The findings of this study revealed that artificial intelligence technology positively influences consumer engagement on social media and conversion rate optimization. Similarly, consumer engagement on social media and conversion rate positively influence satisfying consumer experience, leading to increased consumer repurchase intentions. Finally, consumer habit positively moderates the relationship between satisfying consumer experience and repurchase intention. This study facilitated the understanding of artificial intelligence technology to influence consumer engagement on social media and conversion rate to boost consumer satisfaction and repurchase intention and offers suggestions for developing impeccable service business strategies. Marketers must think about making posts more interesting through videos, images, and animations, which will satisfy consumers, ultimately boosting their desire to use, share, and generate content on social media platforms for hospitality organizations.

Expanded Dengue Syndrome Presenting as Intracranial Hemorrhage, Fever, and Rhabdomyolysis: A Case Report.

Rare clinical manifestations of dengue are included under the expanded dengue syndrome (EDS), with intracranial hemorrhage (ICH) being one of them. We discuss an uncommon presentation of dengue with basal ganglia hemorrhage, hyperthermia, and rhabdomyolysis in a 53-year-old hypertensive female who presented with sudden onset syncope, left-sided weakness, and altered sensorium for days, with high-grade fever and vomiting. The Glasgow coma scale (GCS) score was 5, and the patient was intubated. Noncontrast computerized tomography (NCCT) of the brain revealed right basal ganglia bleeding with intraventricular hemorrhage. Electrocardiography (ECG) revealed sinus tachycardia. The patient had spikes of high-grade fever, rhabdomyolysis, stage III acute kidney disease, and coagulopathy. Dengue IgM antibodies were positive. Treatment was started, and the patient was in the intensive care unit (ICU) for six months, following which she was discharged. Given this, one can speculate on the importance of viral diseases presenting with ICH as these are rare and are diagnosed quite late, which can also prove to be fatal.

Epidemiology of sleeping disorders among doctors during COVID-19 pandemic in Pakistan

Introduction: Novel coronavirus disease or COVID-19, an acute respiratory illness caused by a newly discovered SARS-CoV-2 virus emerged in December 2019. Objectives: The main objective of the study is to find the epidemiology of sleeping disorders among doctors during COVID-19 pandemic in Pakistan. Material and methods: This cross sectional study was conducted in Sir Ganga Ram Hospital Lahore during June 2021 to December 2021. A questionnaire was used to collect the data. Among the topics covered in the survey were questions regarding the quality of one's night's sleep, where one keeps infection control supplies, how one copes with stress and depression, how one learns about COVID-19 on the internet, how one views risk, and other personal information. The survey was completed over the internet. Results: The data was collected from 200 patients. Over half (55.0 percent) were married and under the age of 35. (49.1%). The majority of respondents (57.8%) spend more than two hours a day on social media. The great majority of them came from the upper echelons of the workforce. There were 38.3%, 29.8%, and 29.1%, respectively, of those who reported a worse sleep quality following the onset of COVID-19, according to their weighted proportions. Conclusion: It is concluded that COVID-19 is widely spreading in Pakistani doctors. Mental health disorders and poor sleep quality are more widespread in the medical field because of the heightened danger of exposure during pandemic illnesses.

COVID-19 Infection in Patients with Humoral Immunodeficiency: A Case Series and Literature Review.

Background: The coronavirus 2019 disease (COVID-19) has infected many individuals worldwide and continues to pose a significant threat to those with weakened immune systems. The data evaluating the clinical outcomes of patients with humoral immunodeficiencies that contract COVID-19 is limited and conflicting. Objective: To describe the clinical outcomes of COVID-19 infections in patients with primary humoral immunodeficiency and compare results to current literature. Methods: We conducted a retrospective cohort review on 15 patients with a humoral immunodeficiency defined as Common Variable Immunodeficiency, Specific Antibody Deficiency, or unspecified hypogammaglobulinemia, who contracted COVID-19. Severity scores were determined to evaluate the clinical outcomes of these patients. Results: Of our 15-patient cohort, 33% of individuals with a humoral immunodeficiency infected with COVID-19 had moderate to severe disease, requiring hospitalization or resulting in death. COVID-19 mortality rate was found to be 7%. All 5 of our patients with severe COVID-19 infection had at least 1 comorbidity or risk factor. Conclusion: Within our cohort of humoral immunodeficient patients infected with COVID-19, we found a higher rate of moderate to severe COVID-19 infection and worse clinical outcomes, particularly in patients with comorbidities or risk factors.

Cytomegalovirus Coinfection in Critically Ill Patients with Novel Coronavirus-2019 Disease: Pathogens or Spectators?

Coronavirus disease-2019 (COVID-19) pandemic is raging all over the world. As we are delving more into management of COVID-19, certain new challenges are emerging. One of these is emergence or reactivation of viral infections belonging to Herpesviridae family, especially cytomegalovirus (CMV). Although we have come across the threat of fungal and resistant bacterial infections, experience regarding reactivation or coinfection with concomitant viral infections like CMV during the COVID pandemic is still limited. Whether CMV is a bystander or pathogen is difficult to say categorically and needs further research. In this case series, we intend to describe three patients of COVID-19 with CMV coinfections. To our knowledge, this is the first case series from India. How to cite this article: Siddiqui SS, Chatterjee S, Yadav A, Rai N, Agrawal A, Gurjar M, et al. Cytomegalovirus Coinfection in Critically Ill Patients with Novel Coronavirus-2019 Disease: Pathogens or Spectators? Indian J Crit Care Med 2022;26(3):376-380.

COVID-19 pandemic related excessive electronic media exposure and mental health in Saudi Arabia.

OBJECTIVE: Due to the continued spread of COVID-19 and the emergence of novel mutated viral variants, families all over the world are experiencing wide-ranging stressors that threaten not only their financial well-being but also their physical and mental health. The present study assessed the association between excessive electronic media exposure of pandemic-related news and mental health of the residents of Ha'il Province, Saudi Arabia. The present study also assessed the prevalence of perceived stress, fear of COVID-19, anxiety, depression, and loneliness due to COVID-19-related restrictions in the same population. MATERIALS AND METHODS: A total of 490 residents of Ha'il Province participated in a cross-sectional online survey during a two-month period (March to April 2021). A validated 38-item self-report survey was used to collect the data. RESULTS: Significant associations were reported between excessive electronic media exposure and the prevalence of perceived stress (χ2=140.56; p<.001), generalized anxiety (χ2=74.55; p<.001), depression (χ2=71.58; p<.001), COVID-19-related fear (χ2=24.54; p<.001), and loneliness (χ2=11.46; p<.001). It was also found that participants without depressive symptoms were 0.28 times less likely to have been exposed to excessive electronic media exposure (AOR: 0.28; C.I. 0.16-0.48; p<.001). Similarly, participants with no stress/mild stress were 0.32 times less likely to have been exposed to excessive electronic media exposure (AOR: 0.32; C.I. 0.19-0.52; p<.001). CONCLUSIONS: The findings of the present study suggest an urgent need for educational resilience programs (online and in-person) for susceptible individuals (females, unemployed, urban residents, etc.). Such programs would help them to develop skills to cope with the psychological impact of the COVID-19 pandemic.

Impact of COVID-19 on clinical diagnosis and management of pre-procedural imaging in gastroenterology

Introduction: Choledocholithiasis, the presence of gallstones in the common bile duct (CBD), commonly presents as abdominal pain, jaundice, and an elevated bilirubin and is further evaluated with abdominal ultrasound and consideration of MRCP or ERCP based on clinical predictors. Herein, we describe a novel approach to abdominal pain and hyperbilirubinemia due to SARS-CoV-2 (Covid 19) which led to additional imaging and an incidental malignancy diagnosis. Case Description/Methods: A 52-year old man with a history of chronic hepatitis B virus presented with one week of abdominal pain and jaundice. Admission labs were significant for a total bilirubin of 4.1mg/dL, and positive screening for Covid 19. Abdominal ultrasonography demonstrated a dilated CBD to 1.7cm. His presentation was highly suggestive of choledocolithiasis by ASGE criteria, but ERCP was deferred to abide by hospital-wide precautions at the time. As a result, the patient underwent confirmatory testing with MRCP, which showed no choledocholithiasis but demonstrated a 4.1cm enhancing lesion abutting the pancreatic body. Subsequent abdominal computed tomography found a 3.3cm soft tissue density encasing the celiac axis, suggesting lymphoma. Endoscopic ultrasound (EUS)-guided biopsy of the pancreatic lesion demonstrated an unreported 3.1cm liver mass, which was biopsied. On further review of imaging, the liver mass was not appreciated on ultrasound, CT or MRCP. It was suspected that the hyperbilirubinemia was likely due to this intrahepatic mass, described as poorly differentiated adenocarcinoma. Due to the early diagnosis he was able to be discharged and follow up with oncology to better guide his future directed therapy. Discussion: The Covid 19 pandemic forced all aspects of healthcare to adapt. Given gastroenterology's invasive nature this also encouraged gastroenterologists to consider alternative pathways of treatment aside from the published algorithms in place. This case demonstrates how deviating from the ASGE guidelines resulted in a cascade of diagnostics which led to an eventual malignancy diagnosis which may have been otherwise missed or delayed. Guidelines are established on large sets of data and patient prognostic indicators which to our knowledge have not considered infection status or isolation needs. Further research in this area may result in amending guidelines to address isolation status and reminds practitioners to consider the patient before them and their unique patient needs. (Figure Presented) .

Coronavirus Pandemic: An Update on the Transmission, Diagnosis, Clinical Features and Managment

The novel coronavirus, designated as "Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2), is a new coronavirus that has evolved as a global pandemic recently, and it has created a widespread interest in coronaviruses causing human infections. This article compares the pathogenesis, distribution, clinical characteristics, and treatment of the three highly pathogenic coronaviruses that caused epidemics, namely, "Severe Acute Respiratory Syndrome Coronavirus" (SARS), "Middle East Respiratory Syndrome" (MERS), and SARS-CoV-2. This narrative review is prepared using the data compiled from literature search using relevant MeSH terms. The clinical manifestation of SARS-CoV-2 infection (COVID-19) is mild with relatively low fatality rate than the other two coronaviruses;however, its overall capability to cause explosive spread of the disease and reach a pandemic level is greater. Unlike SARS and MERS, COVID-19 has no accepted treatment protocols at present. Extensive studies and analyses on COVID-19 are necessary before making strong recommendations for or against any particular treatment, although some recent medications have shown great potential. COVID-19 still needs further investigation, where all of the lessons gained from previous outbreaks of SARS and MERS and the experience from the countries that managed COVID-19 seem to be the best approaches to counteract this new global hazard at present until effective preventive vaccines are available in sufficient quantity for mass vaccination programs worldwide.

Impact of ICT on entrepreneurial self-efficacy in emerging economy: Sustaining lock-down during COVID-19 pandemic

BACKGROUND: COVID-19 affected business in Pakistan and micro-entrepreneurs started struggling. ICT facilitates economic competitiveness and help in sustaining long-Term economic growth during and after pandemic. OBJECTIVE: This article investigates the impact of information communication technology (ICT) on entrepreneurial self-efficacy (ESE), social networking (SN) and facilitation to micro-entrepreneurs, during COVID-19 pandemic in Pakistan. METHOD: We used Technology Acceptance Model (TAM) in this work. The original TAM constructs of ease of use and usefulness were tested, and TAM was extended to ICT to study the further outcomes. Data sets were collected online from 398 microentrepreneurs and further analysed by using the Structural Equation Modelling (SEM). RESULTS: The results indicate that survival of micro-entrepreneurs can be achieved through ICT as it is a strong variable which affects social capital building, bridging and self-efficacy, both directly and indirectly. The entrepreneurial activity can be increased through ICT and entrepreneurs can sustain the implications of lock-downs. CONCLUSION: The findings suggested that ICT usage by micro-entrepreneurs during COVID-19 pandemic was influenced by micro-entrepreneurs' perceptions, of ease of use and usefulness. ICT had direct influence on entrepreneurial self-efficacy and social networking. The theoretical and practical implications of the results are also given. © 2021-IOS Press. All rights reserved.

Acute ST-Elevation Myocardial Infarction Before and During the COVID-19 Pandemic: What is the Clinically Significant Difference?

Background In the current coronavirus disease-2019 (COVID-19) pandemic, the pattern of hospital admissions for acute ST-elevation myocardial infarction (STEMI) is changing, and increased mortality and morbidity is being noted in these patients. Cardiac manifestations of COVID-19 are complex and include STEMI, myocarditis, myocardial injury, and cardiomyopathy. The objective of our study was to compare the data of patients with STEMI presenting in COVID-19 versus the non-COVID-19 era.  Methods We analyzed the clinical and angiographic characteristics of STEMI patients undergoing primary percutaneous coronary intervention (PCI) at our center. The primary outcome variables were admission rate for STEMI, mean total ischemic time (TIT), coronary artery disease burden, mean ejection fraction, and in-hospital mortality for three defined groups. Group A consisted of patients who underwent primary PCI from March through April 2020. Group B included patients who underwent primary PCI from January to February 2020. Group C consisted of patients who underwent primary PCI from March to April 2019. We then compared the data among the three groups and calculated any significant p-value (p<.001). Results In Group A, 1139 patients were admitted for primary PCI. The mean admission rate was 18.6 ± 4.36 admissions per day. There were 1535 patients in Group B and an admission rate of 26.01 ± 4.90 (p<.001 compared to Group A). In Group C, there were 1537 patients and an admission rate of 24.8 ± 4.55 (p<.001, compared to Group A). The mean TIT was 429.25±272.16 minutes for Group A, 359.78±148.04 minutes for Group B, and 346.75±207.31 minutes for Group C (p<.001). A higher mortality rate was noted in Group A (COVID-19 era) versus Group C (non-COVID-19 era; p<.001). Conclusions A lower admission rate, higher TIT, and higher mortality rates were noted in patients with acute STEMI during the COVID-19 pandemic compared to the pre-COVID era. During the COVID-19 pandemic, physicians should bear in mind that patients with STEMI have increased mortality and morbidity. Where possible, efforts should be made for timely management of these critical patients to decrease mortality.